Towards the Clinical Application of Phase-Contrast Computed Tomography in Breast Cancer Imaging

Grant number: 1138283 | Funding period: 2018 - 2021

Completed

Abstract

Imaging used for breast cancer screening misses between 15-40% of cancers and uses radiation and painful patient compression. We introduce phase contrast computed tomography, which for the first time clinically since 1895, will exploit X-ray refraction rather than X-ray absorption. Our pilot data demonstrated an increased image signal, offering significantly improved cancer detection, reduced radiation dose and lower tissue compression. This work will include the world-first patient trial.

Related publications (2)

X-ray phase-contrast computed tomography for soft tissue imaging at the imaging and medical beamline (IMBL) of the australian synchrotron

BD Arhatari, AW Stevenson, B Abbey, YI Nesterets, A Maksimenko, CJ Hall, D Thompson, SC Mayo, T Fiala, HM Quiney, ST Taba, SJ Lewis, PC Brennan, M Dimmock, D Häusermann, TE Gureyev

2021-05-01

The Imaging and Medical Beamline (IMBL) is a superconducting multipole wiggler-based beamline at the 3 GeV Australian Synchrotron ..

X-ray phase-contrast computed tomography for full-breast mastectomy imaging at the Australian Synchrotron

BD Arhatari, YI Nesterets, ST Taba, A Maksimenko, CJ Hall, AW Stevenson, D Häusermann, SJ Lewis, M Dimmock, D Thompson, SC Mayo, HM Quiney, TE Gureyev, PC Brennan

2021-01-01

One of the imaging modalities offered by the Imaging and Medical Beamline (IMBL) at the Australian Synchrotron is Xray phase-contr..

University of Melbourne Researchers

Tim Gureyev